Moist Heat Steam, Pre-Filled Syringe Sterilization, Dry Heat, and Depyrogenation Services
Prince Sterilization Services, LLC is a contract sterilization services provide that specializes in moist heat steam, Pre-Filled Syringe Sterilization, an dry heat sterilization and depyrogenation services. At Prince you will find a full suite of sterilization related support to our customers including development/feasibility, validation, and routine processing cycles. Our expert staff is ready to provide case-by-case consultation support when needed. Click here to download a brochure or continue reading below to learn more about our products and services.
- Terminal Sterilization of Drug Products
- It is a regulatory requirement that drug products that can withstand terminal sterilization be terminally sterilized
- Steam sterilization is the sterilization method of choice
- We offer full product support. Development/Feasibility, Engineering, Validation, and Commercial
- Terminal sterilization of liquids in sealed vessels (aseptically filled drug products in vials, IV bags, syringes, blow-fill-seal technologies, and others)
- Moist heat steam sterilization (pulse pre-vac, gravity, and air-over-pressure)
- Plastic bottles and tubing
- Glass vials
- Stoppers and seals
- Cell culture bags
- Manufacturing equipment (scissors, hemostats, forceps, etc.)
- Eco-friendly and non-toxic
- Pre-Filled Syringe Sterilization
- Prince is equipped with state-of-the-art equipment specialized to provide sterilization of pre-filled syringes. Our experts can help establish sterilization cycles with parameters that achieve appropriate sterilization lethality without compromising stopper movement or syringe integrity. If you have a pre-filled syringe that requires sterilization, Prince is ready to support your efforts in development, engineering, validation, and commercial production.
- Dry heat sterilization
- Heat sensitive drug products and other materials
- Liquids in sealed containers/ampoules
- Eco-friendly and non-toxic
- Depyrogenation
- Glass vials
- Manufacturing/process equipment (e.g. stainless steel)
- Water for injection (WFI) rinsing
- Rinsing of materials such as seals, stoppers, and glass vials with WFI prior to sterilization or depyrogenation.
- Prince Advantage™ Our process lowers bioburden, particulate and endotoxin levels as well as removing stubborn and potentially inhibitory residues.


