Contract Sterilization

Moist Heat Steam, Pre-Filled Syringe Sterilization, Dry Heat, and Depyrogenation Services

Prince Sterilization Services, LLC is a contract sterilization services provide that specializes in moist heat steam, Pre-Filled Syringe Sterilization, an dry heat sterilization and depyrogenation services. At Prince you will find a full suite of sterilization related support to our customers including development/feasibility, validation, and routine processing cycles. Our expert staff is ready to provide case-by-case consultation support when needed. Click here to download a brochure or continue reading below to learn more about our products and services.

  • Terminal Sterilization of Drug Products
    • It is a regulatory requirement that drug products that can withstand terminal sterilization be terminally sterilized
    • Steam sterilization is the sterilization method of choice
    • We offer full product support. Development/Feasibility, Engineering, Validation, and Commercial
    • Terminal sterilization of liquids in sealed vessels (aseptically filled drug products in vials, IV bags, syringes, blow-fill-seal technologies, and others)
  • Moist heat steam sterilization (pulse pre-vac, gravity, and air-over-pressure)
    • Plastic bottles and tubing
    • Glass vials
    • Stoppers and seals
    • Cell culture bags
    • Manufacturing equipment (scissors, hemostats, forceps, etc.)
    • Eco-friendly and non-toxic
  • Pre-Filled Syringe Sterilization
    • Prince is equipped with state-of-the-art equipment specialized to provide sterilization of pre-filled syringes. Our experts can help establish sterilization cycles with parameters that achieve appropriate sterilization lethality without compromising stopper movement or syringe integrity. If you have a pre-filled syringe that requires sterilization, Prince is ready to support your efforts in development, engineering, validation, and commercial production.
  • Dry heat sterilization
    • Heat sensitive drug products and other materials
    • Liquids in sealed containers/ampoules
    • Eco-friendly and non-toxic
  • Depyrogenation
    • Glass vials
    • Manufacturing/process equipment (e.g. stainless steel)
  • Water for injection (WFI) rinsing
    • Rinsing of materials such as seals, stoppers, and glass vials with WFI prior to sterilization or depyrogenation.
    • Prince Advantage™ Our process lowers bioburden, particulate and endotoxin levels as well as removing stubborn and potentially inhibitory residues.